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Iron Homeostasis in Mycobacterium tuberculosis: Mechanistic Insights into Siderophore-Mediated Iron Uptake

Mycobacterium tuberculosis requires iron for normal growth but faces a limitation of the metal ion due to its low solubility at biological pH and the withholding of iron by the mammalian host. The pathogen expresses the Fe(3+)-specific siderophores mycobactin and carboxymycobactin to chelate the met...

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Détails bibliographiques
Publié dans:J Bacteriol
Auteur principal: Sritharan, Manjula
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999934/
https://ncbi.nlm.nih.gov/pubmed/27402628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00359-16
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