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Iron Homeostasis in Mycobacterium tuberculosis: Mechanistic Insights into Siderophore-Mediated Iron Uptake

Mycobacterium tuberculosis requires iron for normal growth but faces a limitation of the metal ion due to its low solubility at biological pH and the withholding of iron by the mammalian host. The pathogen expresses the Fe(3+)-specific siderophores mycobactin and carboxymycobactin to chelate the met...

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Publicado en:J Bacteriol
Autor principal: Sritharan, Manjula
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999934/
https://ncbi.nlm.nih.gov/pubmed/27402628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00359-16
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