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Reconstitution and Minimization of a Micrococcin Biosynthetic Pathway in Bacillus subtilis

Thiopeptides represent one of several families of highly modified peptide antibiotics that hold great promise for natural product engineering. These macrocyclic peptides are produced by a combination of ribosomal synthesis and extensive posttranslational modification by dedicated processing enzymes....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Bacteriol
Hauptverfasser: Bennallack, Philip R., Bewley, Kathryn D., Burlingame, Mark A., Robison, Richard A., Miller, Susan M., Griffitts, Joel S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999933/
https://ncbi.nlm.nih.gov/pubmed/27381911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00396-16
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