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The Cytomegalovirus protein pUL37×1 targets mitochondria to mediate neuroprotection

There is substantial evidence that mitochondrial dysfunction plays a significant role in the pathogenesis of Parkinson disease (PD). This contribution probably encompasses defects of oxidative phosphorylation, mitochondrial turnover (mitophagy), mitochondrial derived oxidative stress, and apoptotic...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hong, Chien Tai, Chau, Kai-Yin, Schapira, Anthony H. V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999870/
https://ncbi.nlm.nih.gov/pubmed/27562039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31373
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