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AMPK-independent inhibition of human macrophage ER stress response by AICAR

Obesity-associated insulin resistance is driven by inflammatory processes in response to metabolic overload. Obesity-associated inflammation can be recapitulated in cell culture by exposing macrophages to saturated fatty acids (SFA), and endoplasmic reticulum (ER) stress responses essentially contri...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Boß, Marcel, Newbatt, Yvette, Gupta, Sahil, Collins, Ian, Brüne, Bernhard, Namgaladze, Dmitry
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999824/
https://ncbi.nlm.nih.gov/pubmed/27562249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32111
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