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New generalized poisson mixture model for bimodal count data with drug effect: An application to rodent brief‐access taste aversion experiments

Pharmacodynamic (PD) count data can exhibit bimodality and nonequidispersion complicating the inclusion of drug effect. The purpose of this study was to explore four different mixture distribution models for bimodal count data by including both drug effect and distribution truncation. An example dat...

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Detalhes bibliográficos
Publicado no:CPT Pharmacometrics Syst Pharmacol
Main Authors: Sheng, Y, Soto, J, Orlu Gul, M, Cortina‐Borja, M, Tuleu, C, Standing, JF
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999606/
https://ncbi.nlm.nih.gov/pubmed/27472892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12093
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