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Severe NDE1-mediated microcephaly results from neural progenitor cell cycle arrests at multiple specific stages

Microcephaly is a cortical malformation disorder characterized by an abnormally small brain. Recent studies have revealed severe cases of microcephaly resulting from human mutations in the NDE1 gene, which is involved in the regulation of cytoplasmic dynein. Here using in utero electroporation of ND...

詳細記述

保存先:
書誌詳細
出版年:Nat Commun
主要な著者: Doobin, David J., Kemal, Shahrnaz, Dantas, Tiago J., Vallee, Richard B.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999518/
https://ncbi.nlm.nih.gov/pubmed/27553190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12551
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