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Severe NDE1-mediated microcephaly results from neural progenitor cell cycle arrests at multiple specific stages
Microcephaly is a cortical malformation disorder characterized by an abnormally small brain. Recent studies have revealed severe cases of microcephaly resulting from human mutations in the NDE1 gene, which is involved in the regulation of cytoplasmic dynein. Here using in utero electroporation of ND...
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出版年: | Nat Commun |
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主要な著者: | , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
Nature Publishing Group
2016
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4999518/ https://ncbi.nlm.nih.gov/pubmed/27553190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12551 |
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