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Three novel mutations of APC gene in Chinese patients with familial adenomatous polyposis

Familial adenomatous polyposis (FAP) is an autosomal dominant disorder characterized by the development of hundreds to thousands of colonic adenomas and an increased risk of colorectal cancer. Adenomatous polyposis coli (APC), encoding a large multidomain protein involved in antagonizing the Wnt sig...

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Detalhes bibliográficos
Publicado no:Tumour Biol
Main Authors: Liu, Qi, Li, Xiaoxia, Li, Sen, Qu, Shengqiang, Wang, Yu, Tang, Qingzhu, Ma, Hongwei, Luo, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999466/
https://ncbi.nlm.nih.gov/pubmed/27000756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13277-016-4986-1
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