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Engineering Synthetically Modified Insulin for Glucose-Responsive Diabetes Therapy

Though a suite of different insulin variants have been used clinically to provide greater control over pharmacokinetics, no clinically used insulin can tune its potency and/or bioavailability in a glucose-dependent manner. In order to improve therapy for diabetic patients, a vision has been the deve...

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Detalhes bibliográficos
Publicado no:Expert Rev Endocrinol Metab
Main Authors: Webber, Matthew J., Anderson, Daniel G., Langer, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999256/
https://ncbi.nlm.nih.gov/pubmed/27570535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/17446651.2015.1071187
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