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Microneedle Integrated with Pancreatic Cells and Synthetic Glucose-Signal Amplifiers for Smart Insulin Delivery

An innovative microneedle (MN)-based cell therapy is developed for glucose-responsive regulation of the insulin secretion from exogenous pancreatic β-cells without implantation. One MN patch could quickly reduce blood sugar levels (BGLs) of chemically-induced type 1 diabetic mice and stabilize BGLs...

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Detalhes bibliográficos
Publicado no:Adv Mater
Main Authors: Ye, Yanqi, Yu, Jicheng, Wang, Chao, Nguyen, Nhu-Y, Walker, Glenn M., Buse, John B., Gu, Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4998837/
https://ncbi.nlm.nih.gov/pubmed/26928976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adma.201506025
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