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GLI2 expression levels in radical nephrectomy specimens as a predictor of disease progression in patients with metastatic clear cell renal cell carcinoma following treatment with sunitinib

The aim of the present study was to investigate the role of the Hedgehog signaling pathway in the progression of metastatic clear cell renal cell carcinoma (m-ccRCC) as well as the molecular targets of sunitinib, an inhibitor of multiple tyrosine kinases. A total of 39 patients subjected to radical...

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Publicado en:Mol Clin Oncol
Autores principales: Furukawa, Junya, Miyake, Hideaki, Fujisawa, Masato
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4998152/
https://ncbi.nlm.nih.gov/pubmed/27602218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mco.2016.950
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