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GLI2 expression levels in radical nephrectomy specimens as a predictor of disease progression in patients with metastatic clear cell renal cell carcinoma following treatment with sunitinib

The aim of the present study was to investigate the role of the Hedgehog signaling pathway in the progression of metastatic clear cell renal cell carcinoma (m-ccRCC) as well as the molecular targets of sunitinib, an inhibitor of multiple tyrosine kinases. A total of 39 patients subjected to radical...

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Detalhes bibliográficos
Publicado no:Mol Clin Oncol
Main Authors: Furukawa, Junya, Miyake, Hideaki, Fujisawa, Masato
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4998152/
https://ncbi.nlm.nih.gov/pubmed/27602218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mco.2016.950
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