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Wedelolactone enhances osteoblastogenesis by regulating Wnt/β-catenin signaling pathway but suppresses osteoclastogenesis by NF-κB/c-fos/NFATc1 pathway

Bone homeostasis is maintained by formation and destruction of bone, which are two processes tightly coupled and controlled. Targeting both stimulation on bone formation and suppression on bone resorption becomes a promising strategy for treating osteoporosis. In this study, we examined the effect o...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Liu, Yan-Qiu, Hong, Zhi-Lai, Zhan, Li-Bin, Chu, Hui-Ying, Zhang, Xiao-Zhe, Li, Guo-Hui
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997609/
https://ncbi.nlm.nih.gov/pubmed/27558652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32260
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