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Wedelolactone enhances osteoblastogenesis by regulating Wnt/β-catenin signaling pathway but suppresses osteoclastogenesis by NF-κB/c-fos/NFATc1 pathway

Bone homeostasis is maintained by formation and destruction of bone, which are two processes tightly coupled and controlled. Targeting both stimulation on bone formation and suppression on bone resorption becomes a promising strategy for treating osteoporosis. In this study, we examined the effect o...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Liu, Yan-Qiu, Hong, Zhi-Lai, Zhan, Li-Bin, Chu, Hui-Ying, Zhang, Xiao-Zhe, Li, Guo-Hui
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997609/
https://ncbi.nlm.nih.gov/pubmed/27558652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32260
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