FAM19A4 methylation analysis in self-samples compared with cervical scrapes for detecting cervical (pre)cancer in HPV-positive women

BACKGROUND: High-risk human papillomavirus (hrHPV)-positive women require triage to identify those with cervical high-grade intraepithelial neoplasia and cancer (⩾CIN3 (cervical intraepithelial neoplasia grade 3)). FAM19A4 methylation analysis, which detects advanced CIN and cancer, is applicable to...

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Veröffentlicht in:Br J Cancer
Hauptverfasser: Luttmer, Roosmarijn, De Strooper, Lise M A, Dijkstra, Maaike G, Berkhof, Johannes, Snijders, Peter J F, Steenbergen, Renske D M, van Kemenade, Folkert J, Rozendaal, Lawrence, Helmerhorst, Theo J M, Verheijen, René H M, ter Harmsel, W Abraham, van Baal, W Marchien, Graziosi, Peppino G C M, Quint, Wim G V, Spruijt, Johan W M, van Dijken, Dorenda K E, Heideman, Daniëlle A M, Meijer, Chris J L M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Molecular Diagnostics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997542/
https://ncbi.nlm.nih.gov/pubmed/27415009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.200
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