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Multiple kinase arrest points in the G1 phase of nontransformed mammalian cells are absent in transformed cells.

We have shown that nontransformed mammalian cells arrest early in the G1 phase of the cell cycle when treated with exceedingly low concentrations of the nonspecific kinase inhibitor staurosporine, whereas transformed cells continue to progress through the cell cycle. We have now treated normal or tr...

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Autori principali: Gadbois, D M, Crissman, H A, Tobey, R A, Bradbury, E M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1992
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC49973/
https://ncbi.nlm.nih.gov/pubmed/1528872
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