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Pleiotropic action of CpG-ODN on endothelium and macrophages attenuates angiogenesis through distinct pathways

There is an integral relationship between vascular cells and leukocytes in supporting healthy tissue homeostasis. Furthermore, activation of these two cellular components is key for tissue repair following injury. Toll-like receptors (TLRs) play a role in innate immunity defending the organism again...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wu, Jiahui, Su, Wenru, Powner, Michael B., Liu, Jian, Copland, David A., Fruttiger, Marcus, Madeddu, Paolo, Dick, Andrew D., Liu, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997267/
https://ncbi.nlm.nih.gov/pubmed/27558877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31873
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