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Inositol 1,4,5-tripshosphate receptor, calcium signaling and polyglutamine expansion disorders
Huntington’s disease (HD), spinocerebellar ataxia type 2 (SCA2) and type 3 (SCA3) are autosomal-dominant neurodegenerative disorders. HD is caused by polyglutamine (polyQ) expansion (exp) in the amino-terminal region of a protein huntingtin (Htt) and primarily affects medium spiny striatal neurons (...
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| Publicado no: | Curr Top Membr |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4996668/ https://ncbi.nlm.nih.gov/pubmed/22353486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1063-5823(10)66014-0 |
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