Experimentally‐induced anti‐myeloperoxidase vasculitis does not require properdin, MASP‐2 or bone marrow‐derived C5

Anti‐neutrophil cytoplasmic antibody vasculitis is a systemic autoimmune disease with glomerulonephritis and pulmonary haemorrhage as major clinical manifestations. The name reflects the presence of autoantibodies to myeloperoxidase and proteinase‐3, which bind to both neutrophils and monocytes. Evi...

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Foilsithe in:J Pathol
Main Authors: Freeley, Simon J, Popat, Reena J, Parmar, Kiran, Kolev, Martin, Hunt, Beverley J, Stover, Cordula M, Schwaeble, Willhelm, Kemper, Claudia, Robson, Michael G
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley & Sons, Ltd 2016
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Original Papers
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996338/
https://ncbi.nlm.nih.gov/pubmed/27235854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4754
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