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Experimentally‐induced anti‐myeloperoxidase vasculitis does not require properdin, MASP‐2 or bone marrow‐derived C5

Anti‐neutrophil cytoplasmic antibody vasculitis is a systemic autoimmune disease with glomerulonephritis and pulmonary haemorrhage as major clinical manifestations. The name reflects the presence of autoantibodies to myeloperoxidase and proteinase‐3, which bind to both neutrophils and monocytes. Evi...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Freeley, Simon J, Popat, Reena J, Parmar, Kiran, Kolev, Martin, Hunt, Beverley J, Stover, Cordula M, Schwaeble, Willhelm, Kemper, Claudia, Robson, Michael G
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996338/
https://ncbi.nlm.nih.gov/pubmed/27235854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4754
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