Previously reported PDE3A–SLCO1C1 genetic variant does not correlate with anti-TNF response in a large UK rheumatoid arthritis cohort

AIM: A genetic variant has recently reached genome-wide significance for association with TNF-inhibitor response in rheumatoid arthritis patients. Here we undertake a replication study in a UK Caucasian population to test for association with TNF-inhibitor response. MATERIALS & METHODS: The gene...

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Detalhes bibliográficos
Publicado no:Pharmacogenomics
Main Authors: Smith, Samantha Louise, Plant, Darren, Lee, Xiu Hue, Massey, Jonathan, Hyrich, Kimme, Morgan, Ann W, Wilson, Anthony G, Isaacs, John, Barton, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996314/
https://ncbi.nlm.nih.gov/pubmed/27180831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.16.16
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