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Antimalarial activities of oligodeoxynucleotide phosphorothioates in chloroquine-resistant Plasmodium falciparum.

Synthetic oligonucleotides and their chemical modifications have been shown to inhibit viral and cellular gene expression by sequence-specific antisense hybridization to target mRNAs. We now report that oligodeoxynucleotide phosphorothioates and their nuclease-resistant modifications are effective i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rapaport, E, Misiura, K, Agrawal, S, Zamecnik, P
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1992
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC49963/
https://ncbi.nlm.nih.gov/pubmed/1528864
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