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Free Sialic Acid Acts as a Signal That Promotes Streptococcus pneumoniae Invasion of Nasal Tissue and Nonhematogenous Invasion of the Central Nervous System

Streptococcus pneumoniae (pneumococcus) is a leading cause of bacterial meningitis and neurological sequelae in children worldwide. Acute bacterial meningitis is widely considered to result from bacteremia that leads to blood-brain barrier breakdown and bacterial dissemination throughout the central...

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Библиографические подробности
Опубликовано в: :Infect Immun
Главные авторы: Hatcher, Brandon L., Hale, Joanetha Y., Briles, David E.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995916/
https://ncbi.nlm.nih.gov/pubmed/27354445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01514-15
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