Cigarette Smoke Attenuates the Nasal Host Response to Streptococcus pneumoniae and Predisposes to Invasive Pneumococcal Disease in Mice

Streptococcus pneumoniae is a leading cause of invasive bacterial infections, with nasal colonization an important first step in disease. While cigarette smoking is a strong risk factor for invasive pneumococcal disease, the underlying mechanisms remain unknown. This is partly due to a lack of clini...

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Bibliografische gegevens
Gepubliceerd in:Infect Immun
Hoofdauteurs: Shen, Pamela, Morissette, Mathieu C., Vanderstocken, Gilles, Gao, Yang, Hassan, Muhammad, Roos, Abraham, Thayaparan, Danya, Merlano, Maria, Dorrington, Michael G., Nikota, Jake K., Bauer, Carla M. T., Kwiecien, Jacek M., Labiris, Renee, Bowdish, Dawn M. E., Stevenson, Christopher S., Stämpfli, Martin R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2016
Onderwerpen:
Bacterial Infections
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862724/
https://ncbi.nlm.nih.gov/pubmed/26930709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01504-15
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