Cigarette Smoke Attenuates the Nasal Host Response to Streptococcus pneumoniae and Predisposes to Invasive Pneumococcal Disease in Mice

Streptococcus pneumoniae is a leading cause of invasive bacterial infections, with nasal colonization an important first step in disease. While cigarette smoking is a strong risk factor for invasive pneumococcal disease, the underlying mechanisms remain unknown. This is partly due to a lack of clini...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Shen, Pamela, Morissette, Mathieu C., Vanderstocken, Gilles, Gao, Yang, Hassan, Muhammad, Roos, Abraham, Thayaparan, Danya, Merlano, Maria, Dorrington, Michael G., Nikota, Jake K., Bauer, Carla M. T., Kwiecien, Jacek M., Labiris, Renee, Bowdish, Dawn M. E., Stevenson, Christopher S., Stämpfli, Martin R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862724/
https://ncbi.nlm.nih.gov/pubmed/26930709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01504-15
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