Prognostic impact of programed cell death-1 (PD-1) and PD-ligand 1 (PD-L1) expression in cancer cells and tumor infiltrating lymphocytes in colorectal cancer

BACKGROUND: Colorectal cancer (CRC) is 3rd most commonly diagnosed cancer in males and the second in females. PD-1/PD-L1 axis, as an immune checkpoint, is up-regulated in many tumors and their microenvironment. However, the prognostic value of PD-1/PD-L1 in CRC remains unclear. METHODS: The Cancer G...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Cancer
Auteurs principaux: Li, Yaqi, Liang, Lei, Dai, Weixing, Cai, Guoxiang, Xu, Ye, Li, Xinxiang, Li, Qingguo, Cai, Sanjun
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995750/
https://ncbi.nlm.nih.gov/pubmed/27552968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-016-0539-x
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