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Prognostic impact of programed cell death-1 (PD-1) and PD-ligand 1 (PD-L1) expression in cancer cells and tumor infiltrating lymphocytes in colorectal cancer
BACKGROUND: Colorectal cancer (CRC) is 3rd most commonly diagnosed cancer in males and the second in females. PD-1/PD-L1 axis, as an immune checkpoint, is up-regulated in many tumors and their microenvironment. However, the prognostic value of PD-1/PD-L1 in CRC remains unclear. METHODS: The Cancer G...
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Wydane w: | Mol Cancer |
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Główni autorzy: | , , , , , , , |
Format: | Artigo |
Język: | Inglês |
Wydane: |
BioMed Central
2016
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4995750/ https://ncbi.nlm.nih.gov/pubmed/27552968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-016-0539-x |
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