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How time delay and network design shape response patterns in biochemical negative feedback systems

BACKGROUND: Negative feedback in combination with time delay can bring about both sustained oscillations and adaptive behaviour in cellular networks. Here, we study which design features of systems with delayed negative feedback shape characteristic response patterns with special emphasis on the rol...

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Bibliographic Details
Published in:BMC Syst Biol
Main Authors: Börsch, Anastasiya, Schaber, Jörg
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995745/
https://ncbi.nlm.nih.gov/pubmed/27558510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-016-0325-9
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