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Water exit pathways and proton pumping mechanism in B-type cytochrome c oxidase from molecular dynamics simulations
Cytochrome c oxidase (CcO) is a vital enzyme that catalyzes the reduction of molecular oxygen to water and pumps protons across mitochondrial and bacterial membranes. While proton uptake channels as well as water exit channels have been identified for A-type CcOs, the means by which water and proton...
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| Publié dans: | Biochim Biophys Acta |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4995112/ https://ncbi.nlm.nih.gov/pubmed/27317965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2016.06.005 |
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