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Cytotoxicity of atropine to human corneal endothelial cells by inducing mitochondrion-dependent apoptosis

Atropine, a widely used topical anticholinergic drug, might have adverse effects on human corneas in vivo. However, its cytotoxic effect on human corneal endothelium (HCE) and its possible mechanisms are unclear. Here, we investigated the cytotoxicity of atropine and its underlying cellular and mole...

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Bibliografiske detaljer
Udgivet i:Exp Biol Med (Maywood)
Main Authors: Wen, Qian, Fan, Ting-Jun, Tian, Cheng-Lei
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994923/
https://ncbi.nlm.nih.gov/pubmed/27022135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370216640931
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