Actions of the antihistaminergic clemastine on presymptomatic SOD1-G93A mice ameliorate ALS disease progression

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a disease with a strong neuroinflammatory component sustained by activated microglia contributing to motoneuron death. However, how to successfully balance neuroprotective versus neurotoxic actions by the use of antinflammatory agents is still under...

Full description

Saved in:
Bibliographic Details
Published in:J Neuroinflammation
Main Authors: Apolloni, Savina, Fabbrizio, Paola, Amadio, Susanna, Volonté, Cinzia
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994328/
https://ncbi.nlm.nih.gov/pubmed/27549088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0658-8
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items