Ładuje się......
Harnessing Fluorine–Sulfur Contacts and Multipolar Interactions for the Design of p53 Mutant Y220C Rescue Drugs
[Image: see text] Many oncogenic mutants of the tumor suppressor p53 are conformationally unstable, including the frequently occurring Y220C mutant. We have previously developed several small-molecule stabilizers of this mutant. One of these molecules, PhiKan083, 1-(9-ethyl-9H-carbazole-3-yl)-N-meth...
Zapisane w:
| Wydane w: | ACS Chem Biol |
|---|---|
| Główni autorzy: | , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American
Chemical
Society
2016
|
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4994063/ https://ncbi.nlm.nih.gov/pubmed/27267810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00315 |
| Etykiety: |
Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!
|