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Thyrotropin Receptor Epitope and Human Leukocyte Antigen in Graves’ Disease
Graves’ disease (GD) is an organ-specific autoimmune disease, and thyrotropin (TSH) receptor (TSHR) is a major autoantigen in this condition. Since the extracellular domain of human TSHR (TSHR-ECD) is shed into the circulation, TSHR-ECD is a preferentially immunogenic portion of TSHR. Both genetic f...
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| Publicado no: | Front Endocrinol (Lausanne) |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4994058/ https://ncbi.nlm.nih.gov/pubmed/27602020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2016.00120 |
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