Murine tribbles homolog 2 deficiency affects erythroid progenitor development and confers macrocytic anemia on mice

Tribbles homolog 2 (Trib2) is a member of Tribbles protein pseudokinases and involves in apoptosis, autoimmunity, cancer, leukemia and erythropoiesis, however, the physiological function of Trib2 in hematopoietic system remains to be elucidated. Here, we report that Trib2 knockout (KO) mice manifest...

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Vydáno v:Sci Rep
Hlavní autoři: Lin, Kou-Ray, Yang-Yen, Hsin-Fang, Lien, Huang-Wei, Liao, Wei-Hao, Huang, Chang-Jen, Lin, Liang-In, Li, Chung-Leung, Yen, Jeffrey Jong-Young
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994003/
https://ncbi.nlm.nih.gov/pubmed/27550848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31444
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