Murine tribbles homolog 2 deficiency affects erythroid progenitor development and confers macrocytic anemia on mice

Tribbles homolog 2 (Trib2) is a member of Tribbles protein pseudokinases and involves in apoptosis, autoimmunity, cancer, leukemia and erythropoiesis, however, the physiological function of Trib2 in hematopoietic system remains to be elucidated. Here, we report that Trib2 knockout (KO) mice manifest...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Lin, Kou-Ray, Yang-Yen, Hsin-Fang, Lien, Huang-Wei, Liao, Wei-Hao, Huang, Chang-Jen, Lin, Liang-In, Li, Chung-Leung, Yen, Jeffrey Jong-Young
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994003/
https://ncbi.nlm.nih.gov/pubmed/27550848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31444
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