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Mitochondrial Dysfunction Contributes to Hypertensive Target Organ Damage: Lessons from an Animal Model of Human Disease

Mechanisms underlying hypertensive target organ damage (TOD) are not completely understood. The pathophysiological role of mitochondrial oxidative stress, resulting from mitochondrial dysfunction, in development of TOD is unclear. The stroke-prone spontaneously hypertensive rat (SHRSP) is a suitable...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Rubattu, Speranza, Stanzione, Rosita, Volpe, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993945/
https://ncbi.nlm.nih.gov/pubmed/27594970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1067801
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