Pathogenesis of Target Organ Damage in Hypertension: Role of Mitochondrial Oxidative Stress

Hypertension causes target organ damage (TOD) that involves vasculature, heart, brain and kidneys. Complex biochemical, hormonal and hemodynamic mechanisms are involved in the pathogenesis of TOD. Common to all these processes is an increased bioavailability of reactive oxygen species (ROS). Both in...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Rubattu, Speranza, Pagliaro, Beniamino, Pierelli, Giorgia, Santolamazza, Caterina, Di Castro, Sara, Mennuni, Silvia, Volpe, Massimo
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2014
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4307277/
https://ncbi.nlm.nih.gov/pubmed/25561233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16010823
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