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Shikonin Inhibits Intestinal Calcium-Activated Chloride Channels and Prevents Rotaviral Diarrhea

Secretory diarrhea remains a global health burden and causes major mortality in children. There have been some focuses on antidiarrheal therapies that may reduce fluid losses and intestinal motility in diarrheal diseases. In the present study, we identified shikonin as an inhibitor of TMEM16A chlori...

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Bibliografski detalji
Izdano u:Front Pharmacol
Glavni autori: Jiang, Yu, Yu, Bo, Yang, Hong, Ma, Tonghui
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993765/
https://ncbi.nlm.nih.gov/pubmed/27601995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00270
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