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Identifying a maximum tolerated contour in two-dimensional dose-finding
The majority of Phase I methods for multi-agent trials have focused on identifying a single maximum tolerated dose combination (MTDC) among those being investigated. Some published methods in the area have been based on the notion that there is no unique MTDC, and that the set of dose combinations w...
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| 出版年: | Stat Med |
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| 第一著者: | |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4993696/ https://ncbi.nlm.nih.gov/pubmed/26910586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6918 |
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