Transmembrane Protein 88 (TMEM88) Promoter Hypomethylation is Associated with Platinum Resistance in Ovarian Cancer

OBJECTIVES: Epigenetic alterations have been implicated in the development of platinum resistance in ovarian cancer (OC). In this study, we aimed to identify DNA methylation changes in platinum resistant tumors and their functional implications. METHODS: To identify DNA methylation alterations we us...

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Bibliografiske detaljer
Udgivet i:Gynecol Oncol
Main Authors: de Leon, Maria, Cardenas, Horacio, Vieth, Edyta, Emerson, Robert, Segar, Matthew, Liu, Yunlong, Nephew, Kenneth, Matei, Daniela
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993677/
https://ncbi.nlm.nih.gov/pubmed/27374141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2016.06.017
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