Transmembrane Protein 88 (TMEM88) Promoter Hypomethylation is Associated with Platinum Resistance in Ovarian Cancer

OBJECTIVES: Epigenetic alterations have been implicated in the development of platinum resistance in ovarian cancer (OC). In this study, we aimed to identify DNA methylation changes in platinum resistant tumors and their functional implications. METHODS: To identify DNA methylation alterations we us...

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發表在:Gynecol Oncol
Main Authors: de Leon, Maria, Cardenas, Horacio, Vieth, Edyta, Emerson, Robert, Segar, Matthew, Liu, Yunlong, Nephew, Kenneth, Matei, Daniela
格式: Artigo
語言:Inglês
出版: 2016
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993677/
https://ncbi.nlm.nih.gov/pubmed/27374141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2016.06.017
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