TGF-β induces global changes in DNA methylation during the epithelial-to-mesenchymal transition in ovarian cancer cells

A key step in the process of metastasis is the epithelial-to-mesenchymal transition (EMT). We hypothesized that epigenetic mechanisms play a key role in EMT and to test this hypothesis we analyzed global and gene-specific changes in DNA methylation during TGF-β-induced EMT in ovarian cancer cells. E...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Cardenas, Horacio, Vieth, Edyta, Lee, Jiyoon, Segar, Mathew, Liu, Yunlong, Nephew, Kenneth P, Matei, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622747/
https://ncbi.nlm.nih.gov/pubmed/25470663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15592294.2014.971608
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