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Multiple roles for keratin intermediate filaments in the regulation of epithelial barrier function and apico-basal polarity
As multicellular organisms evolved a family of cytoskeletal proteins, the keratins (types I and II) expressed in epithelial cells diversified in more than 20 genes in vertebrates. There is no question that keratin filaments confer mechanical stiffness to cells. However, such a number of genes can ha...
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| Veröffentlicht in: | Tissue Barriers |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4993576/ https://ncbi.nlm.nih.gov/pubmed/27583190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21688370.2016.1178368 |
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