Claudin-based barrier differentiation in the colonic epithelial crypt niche involves Hopx/Klf4 and Tcf7l2/Hnf4-α cascades

Colonic enterocytes form a rapidly renewing epithelium and barrier to luminal antigens. During renewal, coordinated expression of the claudin family of genes is vital to maintain the epithelial barrier. Disruption of this process contributes to barrier compromise and mucosal inflammatory diseases. H...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Tissue Barriers
Prif Awduron: Lili, Loukia N., Farkas, Attila E., Gerner-Smidt, Christian, Overgaard, Christian E., Moreno, Carlos S., Parkos, Charles A., Capaldo, Christopher T., Nusrat, Asma
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2016
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993572/
https://ncbi.nlm.nih.gov/pubmed/27583195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21688370.2016.1214038
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