Claudin-based barrier differentiation in the colonic epithelial crypt niche involves Hopx/Klf4 and Tcf7l2/Hnf4-α cascades

Colonic enterocytes form a rapidly renewing epithelium and barrier to luminal antigens. During renewal, coordinated expression of the claudin family of genes is vital to maintain the epithelial barrier. Disruption of this process contributes to barrier compromise and mucosal inflammatory diseases. H...

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Detalhes bibliográficos
Publicado no:Tissue Barriers
Main Authors: Lili, Loukia N., Farkas, Attila E., Gerner-Smidt, Christian, Overgaard, Christian E., Moreno, Carlos S., Parkos, Charles A., Capaldo, Christopher T., Nusrat, Asma
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993572/
https://ncbi.nlm.nih.gov/pubmed/27583195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21688370.2016.1214038
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