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IDH1/2 Mutants Inhibit TET-Promoted Oxidation of RNA 5mC to 5hmC
TETs (TET1/2/3) play critical roles in multi cellular processes through DNA demethylation driven by oxidation of DNA 5mdC to 5hmdC. Interestingly, recent studies indicated that TETs also oxidate RNA 5mC to 5hmC. However, little is known about the distribution of RNA 5hmC and the regulatory mechanism...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4993491/ https://ncbi.nlm.nih.gov/pubmed/27548812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161261 |
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