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Role of Tet proteins in 5mC to 5hmC conversion, ES cell self-renewal, and ICM specification
DNA methylation is one of the best-characterized epigenetic modifications (1–4). While the enzymes that catalyze DNA methylation have been characterized, enzymes responsible for the reversal process have been elusive (5). A recent study indicates that the human Tet1 protein could catalyze the conver...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3491567/ https://ncbi.nlm.nih.gov/pubmed/20639862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09303 |
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