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Role of Tet proteins in 5mC to 5hmC conversion, ES cell self-renewal, and ICM specification

DNA methylation is one of the best-characterized epigenetic modifications (1–4). While the enzymes that catalyze DNA methylation have been characterized, enzymes responsible for the reversal process have been elusive (5). A recent study indicates that the human Tet1 protein could catalyze the conver...

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Detaylı Bibliyografya
Asıl Yazarlar: Ito, Shinsuke, D’Alessio, Ana C., Taranova, Olena V., Hong, Kwonho, Sowers, Lawrence C., Zhang, Yi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491567/
https://ncbi.nlm.nih.gov/pubmed/20639862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09303
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