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Applying Fluorescence Resonance Energy Transfer (FRET) to Examine Effector Translocation Efficiency by Coxiella burnetii during siRNA Silencing

Coxiella burnetii, the causative agent of Q fever, is an intracellular pathogen that relies on a Type IV Dot/Icm Secretion System to establish a replicative niche. A cohort of effectors are translocated through this system into the host cell to manipulate host processes and allow the establishment o...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Newton, Patrice, Latomanski, Eleanor A., Newton, Hayley J.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993368/
https://ncbi.nlm.nih.gov/pubmed/27501079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54210
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