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Dose enhancement effects to the nucleus and mitochondria from gold nanoparticles in the cytosol

Gold nanoparticles (GNPs) have shown potential as dose enhancers for radiation therapy. Since damage to the genome affects the viability of a cell, it is generally assumed that GNPs have to localise within the cell nucleus. In practice, however, GNPs tend to localise in the cytoplasm yet still appea...

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Podrobná bibliografie
Vydáno v:Phys Med Biol
Hlavní autoři: McNamara, AL, Kam, WW-Y, Scales, N, McMahon, SJ, Bennett, JW, Byrne, HL, Schuemann, J, Paganetti, H, Banati, R, Kuncic, Z
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993038/
https://ncbi.nlm.nih.gov/pubmed/27435339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/0031-9155/61/16/5993
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