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Dose enhancement effects to the nucleus and mitochondria from gold nanoparticles in the cytosol

Gold nanoparticles (GNPs) have shown potential as dose enhancers for radiation therapy. Since damage to the genome affects the viability of a cell, it is generally assumed that GNPs have to localise within the cell nucleus. In practice, however, GNPs tend to localise in the cytoplasm yet still appea...

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Detalhes bibliográficos
Publicado no:Phys Med Biol
Main Authors: McNamara, AL, Kam, WW-Y, Scales, N, McMahon, SJ, Bennett, JW, Byrne, HL, Schuemann, J, Paganetti, H, Banati, R, Kuncic, Z
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993038/
https://ncbi.nlm.nih.gov/pubmed/27435339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/0031-9155/61/16/5993
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