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Key Targets for Multi-Target Ligands Designed to Combat Neurodegeneration
HIGHLIGHTS: Compounds that interact with multiple targets but minimally with the cytochrome P450 system (CYP) address the many factors leading to neurodegeneration. Acetyl- and Butyryl-cholineEsterases (AChE, BChE) and Monoamine Oxidases A/B (MAO A, MAO B) are targets for Multi-Target Designed Ligan...
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| Publicado no: | Front Neurosci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4992697/ https://ncbi.nlm.nih.gov/pubmed/27597816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2016.00375 |
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