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Chemoattractant receptors BLT1 and CXCR3 regulate antitumor immunity by facilitating CD8(+) T cell migration into tumors

Immunotherapies have shown considerable efficacy for the treatment of various cancers but a multitude of patients remain unresponsive for various reasons including poor homing of T cells into tumors. In this study, we investigated the roles of leukotriene B(4) receptor - BLT1; and CXCR3, the recepto...

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Podrobná bibliografie
Vydáno v:J Immunol
Hlavní autoři: Chheda, Zinal S., Sharma, Rajesh K., Jala, Venkatakrishna R., Luster, Andrew D., Haribabu, Bodduluri
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992661/
https://ncbi.nlm.nih.gov/pubmed/27465528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502376
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